Diabesity - novel molecular targets for obesity and type 2 diabetes

Publications 2005
The following publications have arisen from DIABESITY in 2005:

The endocannabinoid system and the treatment of obesity

Uberto Pagotto, Valentina Vicennatti, Renato Pasquali

Central Responsiveness to a Ghrelin Mimetic (GHRP-6) is Rapidly Altered by Acute Changes in Nutritional Status in Rats
Y. C. L. Tung, A. K. Hewson, R. N. Carter and S. L. Dickson

Neurochemical characterization of hypothalamic neurons involved in attack behavior: Glutamatergic dominance and co-expression of thyrotropin-releasing hormone in a subset of glutamatergic neurons
E Hrabovszky, J Halaszy, W Meelis, M R Kruk,Z Liposits, J Haller

Hypophysiotropic Thyrotropin-Releasing Hormone and Corticotropin-Releasing Hormone Neurons of the Rat Contain Vesicular Glutamate Transporter-2
Erik Hrabovszky, Gabor Wittmann, Gergely F. Turi, Zsolt Liposits, and Csaba Fekete

Sensing the fat: Fatty acid metabolism in the hypothalamus and the melanocortin system
Miguel Lopez, Sulay Tovar, Marıa Jesus Vazquez, Ruben Nogueiras, Rosa Senarıs, Carlos Dieguez

Origin of Cocaine- and Amphetamine-Regulated Transcript-Containing Axons Innervating Hypophysiotropic Corticotropin-Releasing Hormone-Synthesizing Neurons in the Rat
Gabor Wittmann, Zsolt Liposits, Ronald M. Lechan, and Csaba Fekete

Hypothalamic expression of NPY mRNA, vasopressin mRNA and CRF mRNA in response to food restriction and central administration of the orexigenic peptide GHRP-6
Louise E. Johnstone, Rungrudee Srisawat, Ekkasit Kumarnsit and Gareth Leng

Presence of vesicular glutamate transporter-2 in hypophysiotropic somatostatin but not growth hormone-releasing hormone neurons of the male rat
Erik Hrabovszky, Gergely F. Turi and Zsolt Liposits

Glutamatergic innervation of corticotropin-releasing hormone- and thyrotropin-releasing hormone-synthesizing neurons in the hypothalamic paraventricular nucleus of the rat
Gabor Wittmann, Ronald M. Lechanb, Zsolt Liposits, Csaba Fekete

Agouti-related peptide-expressing neurones are essential for feeding
Gropp E, Shanabrough M, Borok E, Xu AW, Janoschek R, Buch T, Plum L, Balthasar N, Hampel B, Waisman A, Barsh GS, Horvath TL, Bruning JC.

Central administration of resistin promotes short-term satiety in rats
Sulay Tovar, Ruben Nogueiras, Loraine Y C Tung, Tamara R Castaneda, Marıa Jesu´s Vazquez,
Amanda Morris, Lynda M Williams, Suzanne L Dickson and Carlos Dieguez

A possible role of neuropeptide Y, agouti-related protein and leptin receptor isoforms in hypothalamic programming by perinatal feeding in the rat
M. López, L. M. Seoane, S. Tovar, M. C. García, R. Nogueiras, C. Diéguez and R. M. Señarís

Fighting obesity and associated risk factors by antagonising cannabinoid type 1 receptors
Uberto Pagotto

Short-term modification of sex hormones is associated with changes in ghrelin circulating levels in healthy normal-weight men
A. Gambineri, U. Pagotto, R. De Lasio, M.C. Meriggiola, A. Costantino, L. Patton, C. Pelusi, G. Pelusi, and R. Pasquali

Increased body fat in mice with a targeted mutation of the paternally expressed imprinted gene Peg3
Curley JP, Pinnock SB, Dickson SL, Thresher R, Miyoshi N, Surani MA & Keverne EB

Lack of the central nervous system- and neural crest-expressed forkhead gene Foxs1 affects motor function and body weight
Heglind M, Cederberg A, Aquino A, Lucas G, Ernfors P and Enerbäck S

Expression and regulation of adiponectin and receptor in human and rat placenta

J. Eduardo Caminos, Rubén Nogueiras, Rosalía Gallego, Susana Bravo, Sulay Tovar, Tomás García-Caballero, Felipe F. Casanueva and Carlos Diéguez

Ghrelin treatment reverses the reduction in weight gain and body fat in gastrectomised mice
Charlotta Dornonville de la Cour, Andreas Lindqvist, Emil Egecioglu, YC Loraine Tung, Vikas Surve, Claes Ohlsson, John-Olov Jansson, Charlotte Erlanson-Albertsson, Suzanne L Dickson, and Rolf Håkanson

A new renal mitochondrial carrier, KMCP1, is up-regulated during tubular cell regeneration and induction of antioxidant enzymes
Anne Haguenauer, Serge Raimbault, Sandrine Masscheleyn, Maria del Mar Gonzalez-Barroso, Francois Criscuolo, Julie Plamondon, Bruno Miroux, Daniel Ricquier, Denis Richard, Frederic Bouillaud and Claire Pecqueur

Adipocyte-specific overexpression of FOXC2 prevents diet-induced increases in intramuscular fatty acyl CoA and insulin resistance
Jason K. Kim, Hyo-Jeong Kim, So-Young Park, Anna Cederberg, Rickard Westergren, Daniel Nilsson, Takamasa Higashimori, You-Ree Cho, Zhen-Xiang Liu, Sven Enerback, & Gerald I. Shulman

Diabesity: Novel molecular targets for obesity and type 2 diabetes
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